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. 2018 Jun 25;18:681. doi: 10.1186/s12885-018-4526-z

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© The Author(s). 2018

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 6 — The expression level of Cbl-b protein in tissue samples of 100 patients with PDAC was detected by immunohistochemical method. (A) We analyzed the role of Cbl-b in pancreatic cancer, the results showed that the expression level of Cbl-b was significantly negative correlated with the prognosis of pancreatic cancer. (B) Immunohistochemical method detect the level of Cbl-b. (a) Cbl-b negative staining, (b, c) Cbl-b moderate and strong staining in cell membrane and cytoplasm (in brown). The original magnification is 200×