Table 2.

Between, within, and indirect effect estimates (with Bayesian credibility intervals) from a multilevel structural equation model analysis predicting total grams of cannabis smoked on a given smoking day from medication condition and putative mediators

Parameter	Est.	Posterior SD	pa	[95% CI]b
Between
Conditionc → M (a between)
High	-1.27	0.59	<.001	[-2.62, -0.06]*
Craving	-1.21	0.90	.060	[-2.91, 0.46]
Stimulation	2.06	1.49	.100	[-1.01, 4.62]
Sedation	-1.35	0.79	.270	[-4.48, 1.84]
Stress	-0.12	0.81	.410	[-1.64, 1.41]
M → Total grams (b between)
High	0.38	0.11	<.001	[0.19, 0.59]*
Craving	-0.18	0.05	<.001	[-0.28, -0.07]*
Stimulation	-0.08	0.04	.010	[-0.16, -0.01]*
Sedation	-0.10	0.02	<.001	[-0.16, -0.06]*
Stress	0.01	0.06	.440	[-0.08, 0.14]
Condition → Total grams (c′)	-0.42	0.0	.210	[-0.93, 0.49]
Within
M → Total grams (b within)
High	-0.01	0.04	.440	[-0.10, 0.06]
Craving	0.06	0.04	.100	[-0.02, 0.13]
Stimulation	0.02	0.03	.310	[-0.03, 0.07]
Sedation	-0.03	0.02	.060	[-0.07, 0.01]
Stress	-0.05	0.03	.020	[-0.01, 0.01]
Grams smoked this event → M
High	1.62	0.72	<.001	[0.24, 3.13]*
Craving	-0.70	0.62	.090	[-1.98, 0.40]
Stimulation	-0.42	1.02	.370	[-2.45, 1.56]
Sedation	3.11	1.35	.030	[1.07, 6.29]*
Stress	-1.44	0.76	.020	[-2.76, -0.17]*
Grams this event → Total grams	0.76	0.44	.020	[0.12, 1.91]*
Indirect effects (a × b)
High	-0.46	0.32	<.001	[-1.29, -0.04]*
Craving	0.21	0.19	.060	[-0.07, 0.62]
Stimulation	-0.12	0.17	.110	[-0.42, 0.09]
Sedation	0.14	0.19	.270	[-0.23, 0.47]
Stress	0.00	0.06	.470	[-0.09, 0.09]

Notes: Normal prior distributions were specified with a mean of zero and prior variance that was infinitely large; median posterior point estimates were specified. Est. = estimate; CI = credibility interval; p = Bayesian one-tailed p value; M = mediator. ^aFor positive values, the Bayesian one-tailed p value is the proportion of the posterior distribution below zero; for negative values, the Bayesian one-tailed p value is the proportion of posterior distribution above zero. ^bThe final column shows the 2.5 and 97.5 percentiles in the posterior distribution; intervals that do not include zero are noted with an asterisk (*). ^cCondition is coded such that 0 = placebo and 1 = topiramate.