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. 2018 Jun 26;24:33. doi: 10.1186/s10020-018-0027-4

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© The Author(s) 2018

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 2 — Schematic presentation of the signalling pathways by which HDAC6 contributes to cyst growth by promoting cell proliferation and fluid secretion induced by aberrant Ca2+ signalling, abnormal cAMP signalling, and prolonged EGFR signalling