Table 4.
Haplotype | case(frequency) | control(frequency) | P-value | OR(95% CI) |
---|---|---|---|---|
C G G | 323.66 (0.680) | 852.26 (0.670) | 0.745 | 1.039 [0.826~ 1.306] |
G A A | 103.66 (0.218) | 324.60 (0.255) | 0.099 | 0.809 [0.629~ 1.041] |
G GG | 42.34 (0.089) | 74.71 (0.059) | 0.025* | 1.561 [1.054~ 2.312] |
Global result | 0.034 |
Abbreviations: OR odds ratio, CI confidence interval
Loci chosen for haplotype analysis: rs10774909, rs229305, rs2682826
Haplotype frequency < 0.01 in both control & case has been dropped
*After Bonferroni correction, p = 0.075