Table 4.
Measurement period | N | CAT | CAT Standardized | CCQ Total | CCQ Total Standardized | SGRQ Total |
---|---|---|---|---|---|---|
15-point GRC T1-T0 | 196 | −3.1*±5.3 (− 3.9 to − 2.4) |
− 7.8*±13.2 (− 9.7 to − 5.9) |
−0.6*±0.8 (− 0.7 to − 0.4) |
− 9.3*±14.0 (− 11.3 to − 7.3) |
− 8.4*±11.8 (− 10.1 to − 6.7) |
15-point GRC T2-T0 | 107 | −2.7*±6.4 (− 4.0 to − 1.5) |
−6.9*±16.1 (− 9.9 to − 3.8) |
−0.4*±1.0 (− 0.6 to − 0.2) |
− 7.3*±16.8 (− 10.5 to − 4.0) |
− 7.6*±13.8 (− 10.2 to − 4.9) |
15-point GRC T3-T0 | 96 | − 2.7*±6.7 (− 4.1 to − 1.4) |
−6.8*±16.7 (− 10.2 to − 3.5) |
−0.4*±1.1 (− 0.6 to − 0.2) |
− 7.0*±18.0 (− 10.6 to − 3.3) |
− 9.2*±14.0 (− 12.1 to − 6.3) |
15-point GRC T4-T0 | 80 | −2.3*±6.1 (− 3.7 to − 1.0) |
−5.8*±15.2 (− 9.2 to − 2.4) |
−0.5*±0.8 (− 0.7 to − 0.3) |
− 7.6*±13.8 (− 10.8 to − 4.7) |
− 10.3*±12.9 (− 13.2 to − 7.4) |
15-point GRC T5-T0 | 88 | −2.8*±6.7 (− 4.2 to − 1.4) |
−7.0*±16.7 (− 10.5 to − 3.5) |
− 0.5*±1.0 (− 0.7 to − 0.3) |
− 8.3*±16.3 (− 11.7 to − 4.8) |
− 8.8*±14.1 (− 11.8 to − 5.8) |
Five-point GRC T5-T0 | 81 | −1.4*±5.9 (− 2.7 to − 0.1) |
−3.5*±14.7 (− 6.7 to − 0.3) |
−0.3*±0.8 (− 0.5 to − 0.2) |
− 5.5*±13.8 (− 8.7 to − 2.5) |
−7.7*±12.9 (− 10.5 to − 4.8) |
Minimal change scores reported as mean ± SD (95%CI). Change is measured compared to baseline. Negative values represent improvement for CAT, CCQ and SGRQ. CAT and CCQ were standardized into a scale from zero to 100 to be comparable with SGRQ
*Significance of change scores p < 0.05 at T1/T2/T3/T4/T5 compared to baseline (T0)
95%CI 95% Confidence Interval, CAT COPD Assessment Test, CCQ Clinical COPD Questionnaire, GRC Global Rating of Change scale, N number of patients, SD Standard Deviation, SGRQ St. George’s Respiratory Questionnaire, T0 Measurement at baseline, T1 Measurement at discharge, T2 3 months follow-up, T3 6 months follow-up, T4 9 months follow-up, T5 12 months follow-up