Fig. 2.

RNS System implantation and recordings.

(a) 3D reconstruction showing location of RNS System electrodes (red dots). Insular cortex is colored in blue for reference. (b) Coronal T1 brain MRI co-registered with post-operative head CT to show location of RNS depth lead in the region of the presumed FCD (compare Fig. 1b). (c) RNS System ECoG capturing a seizure before responsive stimulation was enabled. (d) RNS System ECoG showing putative seizure termination by responsive stimulation. As in (c), low-voltage fast activity arises from the lesional depth electrode channels but, following delivery of responsive therapy (vertical blue line), an ictal pattern does not develop.