Table I.
Clinicopathological characteristics of patients in the TCGA and FUSCC cohorts.
| Variables | TCGA cohort | FUSCC cohort |
|---|---|---|
| Total number of patients, n (%) | 509 | 192 |
| Median age (range), years | 61 (26–90) | 55.5 (17–84) |
| Sex, n (%) | ||
| Male | 328 (64.44) | 131 (68.23) |
| Female | 181 (35.56) | 61 (31.77) |
| Fuhrman grade, n (%) | ||
| 1 and 2 | 234 (45.97) | 79 (41.15) |
| 3 and 4 | 271 (53.24) | 113 (58.85) |
| Gx | 4 (0.79) | 0 (0.00) |
| Mean longest dimension (range), cm | 5.30 (0–20.0) | 5.01 (1–16.0) |
| T, n (%) | ||
| T1 | 258 (50.69) | 129 (67.19) |
| T2 | 63 (12.38) | 29 (15.10) |
| T3 | 178 (34.97) | 27 (14.06) |
| T4 | 10 (1.96) | 7 (3.64) |
| N, n (%) | ||
| N0 | 228 (44.79) | 181 (94.27) |
| N1 | 18 (3.54) | 4 (2.08) |
| Nx | 263 (51.67) | 7 (3.64) |
| M, n (%) | ||
| M0 | 406 (79.76) | 184 (95.80) |
| M1 | 78 (15.32) | 7 (3.60) |
| Mx | 25 (4.91) | 1 (0.50) |
| Stage, n (%) | ||
| I | 253 (49.71) | 130 (67.71) |
| II | 51 (10.02) | 30 (15.62) |
| III | 125 (24.56) | 23 (11.98) |
| IV | 80 (15.72) | 9 (4.69) |
| Laterality, n (%) | ||
| Left | 239 (46.95) | 90 (46.87) |
| Right | 269 (52.85) | 94 (48.95) |
| Bilateral | 1 (0.20) | 8 (41.67) |
| Median hemoglobin (range), g/l | 139 (76–398) | |
| Elevated, n (%) | 5 (0.98) | 20 (10.42) |
| Normal, n (%) | 175 (34.38) | 86 (44.79) |
| Low, n (%) | 251 (49.31) | 16 (8.33) |
| Undefined, n (%) | 78 (15.32) | 70 (36.46) |
| Median white blood cell count (range), 109/l | 6.2 (3.1–18.4) | |
| Elevated, n (%) | 160 (31.43) | 3 (1.56) |
| Normal, n (%) | 251 (49.31) | 100 (52.08) |
| Low, n (%) | 8 (1.57) | 17 (8.85) |
| Undefined, n (%) | 89 (17.49) | 72 (37.5) |
| Median platelet level (range), 109/l | 219 (97–450) | |
| Elevated, n (%) | 35 (6.88) | 4 (2.08) |
| Normal, n (%) | 342 (67.19) | 103 (53.65) |
| Low, n (%) | 45 (8.84) | 2 (1.04) |
| Undefined, n (%) | 86 (16.90) | 83 (43.23) |
| Median follow-up time (range), days | 1,063 (2–3,668) | 1,412 (117–2,245) |
| Median serum LDH level (range), U/la | 155 (67–761) |
a
No data present in the TCGA database. TCGA, The Cancer Genome Atlas; FUSCC, Fudan University Shanghai Cancer Centre; Gx, grade cannot be assessed; T, tumour; N, node; M, metastasis; LDH, lactate dehydrogenase.