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. 2018 May 16;16(1):931–939. doi: 10.3892/ol.2018.8713

Figure 6.

Figure 6.

Schematic diagram illustrating the mechanism of KFX pro-apoptotic effects on SGC-7901 cells through inhibition of the MEK/ERK signaling pathway. MEK, mitogen-activated protein kinase/extracellular-signal-regulated kinase kinase; KFX, Kangfuxin; p-ERK, phosphorylated extracellular signal-regulated kinase; c-caspcase-3, cleaved caspase-3; p53, tumor protein p53; Bcl-2, B-cell lymphoma 2; Bax, Bcl-2 associated X; IL, interleukin; TNF, tumor necrosis factor; PPAR-γ, peroxisome proliferator-activated receptor.