Table 2.
Characteristics of Matched Cohort
| Variable | Quasi-control* | Quasi-treatment† | Standardized Difference | P Value‡ |
|---|---|---|---|---|
| n | 83 | 83 | n/a | n/a |
| Fluid overload %, mean (SD) | 2.86 (1.8) | 8.9 (2.1) | 1.67 | <0.001 |
| Age, yr, mean (SD) | 12.7 (3.9) | 12.1 (4.0) | 0.15 | 0.217 |
| BMI, kg/m2, mean (SD) | 24.3 (7.4) | 23.7 (8.1) | 0.08 | 0.635 |
| Season, n (%) | ||||
| Spring | 31 (37) | 32 (39) | n/a | 0.999 |
| Summer | 17 (20) | 19 (23) | n/a | 0.851 |
| Fall | 25 (30) | 21 (25) | n/a | 0.603 |
| Winter | 10 (12) | 11 (13) | n/a | 0.999 |
| High-dose ICS, n (%)§ | 61 (73) | 60 (72) | n/a | 0.999 |
| Heart rate, median (SD)|| | 110.1 (17.0) | 112.8 (14.8) | −0.13 | 0.268 |
| Bicarbonate, mean (SD)¶ | 19.0 (1.8) | 18.7 (2.1) | 0.15 | 0.266 |
| Severity score, mean (SD)** | 9.0 (1.7) | 9.1 (1.5) | −0.06 | 0.64 |
| ICU admission, n (%) | 53 (64) | 57 (69) | n/a | 0.623 |
Definition of abbreviations: BMI = body mass index; ICS = inhaled corticosteroids; n/a = not applicable.
*
Peak fluid overload less than 7%.
†
Peak fluid overload greater than or equal to 7%.
‡
Paired t test or chi-square test for continuous or categoric variables, respectively.
§
High dose according to Expert Panel Report 3 (33).
||
During first 12 hours of hospital encounter.
¶
First measured value for hospital encounter.
**
Hospital Asthma Severity Score, see Methods.