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. Author manuscript; available in PMC: 2018 Jun 27.
Published in final edited form as: IEEE Trans Biomed Eng. 2016 Sep 22;64(7):1524–1534. doi: 10.1109/TBME.2016.2612639

Fig. 3.

Fig. 3

Proposed nonlinear arterial tube-load model technique for estimation of PTT as a function of BP from proximal and distal BP waveforms. The nonlinear model accounts for BP-dependent arterial compliance and peripheral wave reflection (top panel). The parameters [α (degree of BP-dependence), G, fc] are estimated by finding the finite-difference relationship (see the Appendix) that optimally fits Pp (t) to Pd (t) (middle panel). PTT as a function of BP [Td (P)] is then given via the α estimate and D2LC0 (bottom panel). Note that D2LC0 is specified by the α estimate, the TdMP estimate via the linear arterial tube-load model technique, and MP (middle panel).