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. 2018 May 17;16(1):853–860. doi: 10.3892/ol.2018.8735

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Copyright: © Qu et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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Figure 5. — Upregulation of SPARC reverses the inhibitory effects of miR-211. (A and B) HeLa and C33A cells were co-transfected with control miR (miR-control) or miR-211 either with vector control or SPARC and the expression of SPARC was checked by RT-qPCR. (C and D) CCK-8 assay was conducted in HeLa and C33A cell lines. (E and F) Transwell assay was performed in HeLa and C33A cells lines in different conditions. **P<0.01; *P<0.05; SPARC, secreted protein acidic and rich in cysteine; RT-qPCR, reverse transcription-quantitative polymerase chain reaction; CCK-8, Cell Counting kit-8.