Scgb1a1/CC10 -Cre X RelACKO mice were pretreated with oil (control) or TMX 21 d prior to experimentation. For poly(I:C) challenge, mice were administered either 50 µL of PBS or 50 µL PBS + 100 µg poly(I:C) via the i.n. route. (A). Hematoxylin and Eosin (H&E) staining (upper panel), immunofluorescence staining of phospho-276 RelA, (middle panel, in red color) and immunofluorescence staining of H3K122 Ac (lower panel, in green color) were performed on paraffin-embedded lung sections. (B). Quantifications of total fluorescence intensities on immunofluorescence staining of phospho-276 RelA and H3K122 Ac. * p<0.01, n = 5.