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. Author manuscript; available in PMC: 2019 May 15.
Published in final edited form as: Sci Total Environ. 2017 Dec 27;624:1348–1359. doi: 10.1016/j.scitotenv.2017.12.175

Table 5.

Biological pathways significantly affected by pesticide treatments in frogs.

Pathway Hits Total p-Value
Herbicide treatments
Galactose metabolisma 5 26 0.0004
Starch and sucrose metabolisma 4 19 0.001
Aminoacyl-tRNA biosynthesisa 7 69 0.0013
Alanine, aspartate and glutamate metabolisma 4 24 0.0026
Cysteine and methionine metabolisma 4 27 0.0041
Purine metabolism 5 68 0.026
Inositol phosphate metabolism 3 28 0.0319
Glycine, serine and threonine metabolism 3 31 0.0416
Mixed pesticide treatments
Aminoacyl-tRNA biosynthesisa 13 67 0
Galactose metabolisma 7 26 0
Alanine, aspartate and glutamate metabolisma 6 24 0.0001
Arginine and proline metabolism 7 43 0.0006
beta-Alanine metabolism 4 16 0.0019
Glutathione metabolism 4 26 0.0122
Pyrimidine metabolism 5 41 0.0136
Pantothenate and CoA biosynthesis 3 15 0.0145
Cysteine and methionine metabolisma 4 29 0.0179
Sulfur metabolism 2 9 0.0386
Starch and sucrose metabolisma 3 22 0.0413
Pyruvate metabolism 3 22 0.0413
a

Indicates a pathway shared between both herbicide & mixed pesticide studies.