Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Analysis of IGF-II autocrine signaling in Hep3B and HepG2 cells following DX-2647 treatment. (A) Immunoprecipitation analysis of IR and IGF-IR from cell lysates treated with vehicle or 20 μg/ml DX-2647 for 48 hours followed by blotting for total IR, total IGF-IR, and pan-phosphotyrosine (p-Y99). (B) Western blotting of IR and IGF-IR receptor status and downstream signaling status in cell lysates isolated from Hep3B and HepG2 cells treated with vehicle or 20 μg/ml DX-2647 for 48 hours.
