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. 2018 Jun 25;12:73. doi: 10.1186/s13065-018-0440-3

Table 3.

Anticancer activity results of the synthesized bis-pyrimidine molecules

Anticancer activity (IC50 = µmol/mL)
Compound no. Cancer cell line (HCT-116) Compound no. Cancer cell line (HCT-116)
s1. 12.56 s10. 5.08
s2. 5.16 s11. 2.96
s3. 1.16 s12. 4.44
s4. 13.16 s13. 4.27
s5. 11.79 s14. 3.77
s6. 12.22 s15. 2.63
s7. 6.72 s16. 2.18
s8. 4.91 s17. 2.64
s9. 3.81 s18. 3.59
5-Fluorouracil 0.83 5-Fluorouracil 0.83

HCT-116 human colorectal carcinoma