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. 2018 Mar 3;8:90–94. doi: 10.1016/j.bonr.2018.03.001

Fig. 1.

Fig. 1

Double immunohistochemical staining for osteonectin and BrdU to identify BrdU-positive osteoblasts active in matrix synthesis. Osteonectin-positive osteoblasts stained with Fast Red line the cancellous bone surfaces in a Scl-Ab–treated rat, with a BrdU-positive osteoblast (blue arrow, original magnification 400×). BrdU = 5-bromo-2′-deoxyuridine; Scl-Ab = sclerostin antibody.