Table 1.
Effect of Tsc1 ablation on bone length and growth plate histology at 16 days of age.
| Cre negative Tsc1 fl/fl |
Col2-Cre positive Tsc1 fl/fl |
p-Value | |
|---|---|---|---|
| Value (n) | Value (n) | ||
| Body mass (g) | 6.00 ± 0.14 (5) | 6.03 ± 0.07 (3) | 0.867 |
| Tibial length (mm) | 11.88 ± 0.11 (5) | 11.52 ± 0.08 (3) | 0.070 |
| Femoral length (mm) | 8.45 ± 0.13 (5) | 8.58 ± 0.02 (2) | – |
| Growth plate height (um) | 305.2 ± 17.9 (3) | 324.5 ± 30.8 (3) | 0.616 |
| Hypertrophic zone height (um) | 133.0 ± 7.0 (3) | 142.2 ± 10.8 (3) | 0.511 |
| Terminal hypertrophic cell size (um) | 24.0 ± 0.9 (3) | 24.8 ± 0.6 (3) | 0.532 |