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. 2018 Jun 26;18:151. doi: 10.1186/s12886-018-0821-3

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© The Author(s). 2018

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 9 — The exclusively involved KEGG pathway and 7 proteins detected by the String database. Complement factor H is an isolated one which has no interaction with other proteins. Complement factor D (CFD) and C4b-binding protein alpha chain interacts mutually and exclusively. Furthers, kallikrein B1 interplays highly with Kininogen-1 and Kininogen-1 has interaction with Fibrinogen alpha chain (FGA) and CFD. Meanwhile, FGA and CFD also interacts