Table 4.
Linear regression models, immune markers associated with the Hamilton rating scale of depression
| Bivariate linear reg. Models | Linear regression model assessing five immune markers simultaneously with HRSD-17 | |||||
|---|---|---|---|---|---|---|
| Unadjusted | Adjusteda | |||||
| Immune markers | Reg. coef. (SE) | p-value | Reg. coef. (SE) | p-value | Reg. coef. (SE) | p-value |
| IL-1β.b | 7.2 (1.1) | < 0.001 | 3.1 (2.2) | 0.157 | 3.7 (2.2) | 0.101 |
| IL-7.b | 3.2 (0.5) | < 0.001 | 1.7 (0.7) | 0.017 | 1.5 (0.7) | 0.059 |
| MCP-1.b | 8.9 (1.9) | < 0.001 | 2.4 (1.9) | 0.212 | 3.0 (2.0) | 0.146 |
| TNF.b | 2.6 (0.7) | < 0.001 | −2.5 (1.0) | 0.015 | −2.5 (1.0) | 0.017 |
| VEGF.b | 1.8 (0.2) | < 0.001 | 1.2 (0.4) | 0.002 | 1.1 (0.4) | 0.005 |
Abbreviations: HRSD-17 Hamilton rating scale of depression, CIRS-G cumulative illness rating scale for geriatric patients, BMI body mass index, Reg regression, coef coefficient, SE standard error, IL interleukin, MCP-1 monocyte chemotactic protein, TNF tumour necrosis factor, VEGF vascular endothelial growth factor
aAdjusted for age, gender, CIRS-G (continuous) and BMI
bLN transformed.