Table 2.
Participant No. Age/Gender | Initial Diagnosis ICD-10 31 | Duration of Untreated Psychosis (Days) | Symptoms | Antibody | Seizure | CSF | Initial EEG | MRI |
---|---|---|---|---|---|---|---|---|
1. 28, F | Substance-induced psychosis (cannabis) | 7 | Acute confusion, headaches, hallucinations, agitation, catatonia, encephalopathy with reduction in level of consciousness 8 days after psychosis onset | NMDAR | Yes | WCC 50, Prot 360, NMDAR+ | Normal | Normal |
2. 16, F | Acute and transient psychotic disorder | 5 | Agitation, confusion, seizures, encephalopathy with seizures 9 days after onset of first symptoms | NMDAR | Yes | WCC 15, Prot 370, OCB+, NMDAR+ | Fast background, right temporal slow | Normal |
3. 13, M | Schizophreniform disorder | 70 | Irritable, confusion, labile mood, hallucinations | NMDAR | No | WCC 1, Prot 160, OCB+, NMDA low+ | ND | Normal |
4. 33, M | Bipolar affective disorder | 2 | Suicidal thoughts, delusional thoughts, hallucinations, depressed mood | NMDAR | No | WCC 35, Prot 450, OCB–, NMDA– | Normal | Normal |
5. 16, M | First episode of psychosis | 2 | Bizarre behaviour, thought disorder | VGKC | No | WCC 2, Prot 340, OCB–, NMDA– | Diffuse slowing of background | Normal |
6. 23, M | First episode of psychosis | 7 | Mania, psychosis | Unknown | No | ND | Normal | ND, Head computed tomography scan normal |
CSF, cerebrospinal fluid; EEG, electroencephalogram; F, female; M, male; MRI, magnetic resonance imaging; ND, not done; NMDAR, N-methyl-D-aspartate receptor antibody; OCB, oligoclonal bands; Prot, protein; VGKC, voltage-gated potassium channel antibody; WCC, white cell count.