Table 3.
Overview of antipsychotic and immunotherapy and treatment response
| Patient No. Age/Gender |
Initial Psychotropic Therapy and Response | Time of Initiation of Immunotherapy | Duration of Follow-Up and Treatment Response |
|---|---|---|---|
| 1. 28, F | Olanzapine and diazepam for 6 days. No improvement with medications. Some sedation with fluctuation in mental state | Immunotherapy commenced 6 days after admission for
psychosis. Teratoma removal, IVMP, IVIg, RTX. |
3 years and 9 months: no psychosis. Some symptoms of depression and anxiety. Working full time |
| 2. 16, F | Olanzapine and diazepam for 4 days. Some reduction in agitation with psychotropic medication | Immunotherapy commenced 4 days after admission for
psychosis. Teratoma removal, IVMP, IVIg, RTX |
2 years and 9 months: no psychosis. Some social difficulties following illness. Attending university |
| 3. 13, M | Olanzapine for 7 days with no improvement | Immunotherapy commenced 7 days after
admission. IVMP, IVIg |
2 years and 6 months: no psychosis. Sleep problems and fluctuating mood. Unemployed |
| 4. 33, M | Initially risperidone and mirtazapine. Akathisia experienced, and risperidone ceased. Commenced on quetiapine. No response after 6 days | Immunotherapy commenced 6 days after admission to
hospital. IVMP, IVIg, AZA |
1 year and 6 months: no psychosis. Persistent symptoms of depression and anxiety. Working full time |
| 5. 16, M | Risperidone with minimal improvement after 22 days | Immunotherapy commenced 22 days after admission to
hospital. IVIg, IVMP |
2 year and 6 months: good response to IVMP. Relapsing course. Remains on olanzapine. Attending school full time |
| 6. 23, M | Risperidone | No immunotherapy | 1 month: remission from psychosis |
AZA, azathioprine; IVIg, intravenous immunoglobulins; IVMP, intravenous methylprednisolone; RTX, rituximab.