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. 2018 Jun 26;9(3):e01153-18. doi: 10.1128/mBio.01153-18

TABLE 3 .

Retention of infectivity by in vitro-cultured T. pallidum Nichols

T. pallidum
dosage per site
No. of lesions/
no. of sites inoculated
Day of lesion
development
Avg day of lesion
development
Experiment A: inoculum = 45-day culture
460,000 4/4 7, 7, 7, 7 7.0
100,000 4/4 8, 8, 8, 8 8.0
10,000 4/4 9, 11, 11, 11 10.5
100 3/4 18, 19, 20 19.0
10 2/4 21, 26 23.5
Experiment B: inoculum = 116-day culture
10,000 6/6 11, 11, 11, 11, 11, 12 11.2
1,000 6/6 11, 11, 11, 11, 11, 12 11.2
100 6/6 14, 16, 16, 17, 17, 18 16.3
10 6/6 23, 24, 24, 25, 29, 29 25.7
1 3/6 19, 36, 36 30.3