Table 2.
The significantly enriched KEGG pathways (with P < 0.05) based on the differentially expressed mRNAs
| Pathway Id | pathway description | S gene number | TS gene number | B gene number | TB gene number | P value |
|---|---|---|---|---|---|---|
| ko00190 | Oxidative phosphorylation | 34 | 579 | 88 | 3735 | 0.00 |
| ko00280 | Valine, leucine and isoleucine degradation | 19 | 579 | 42 | 3735 | 0.00 |
| ko01200 | Carbon metabolism | 30 | 579 | 88 | 3735 | 0.00 |
| ko03030 | DNA replication | 13 | 579 | 27 | 3735 | 0.00 |
| ko00640 | Propanoate metabolism | 13 | 579 | 28 | 3735 | 0.00 |
| ko03320 | PPAR signaling pathway | 19 | 579 | 51 | 3735 | 0.00 |
| ko00630 | Glyoxylate and dicarboxylate metabolism | 12 | 579 | 26 | 3735 | 0.00 |
| ko01230 | Biosynthesis of amino acids | 19 | 579 | 53 | 3735 | 0.00 |
| ko00620 | Pyruvate metabolism | 13 | 579 | 31 | 3735 | 0.00 |
| ko00071 | Fatty acid degradation | 12 | 579 | 29 | 3735 | 0.00 |
| ko04216 | Ferroptosis | 12 | 579 | 30 | 3735 | 0.00 |
| ko00260 | Glycine, serine and threonine metabolism | 12 | 579 | 33 | 3735 | 0.00 |
| ko00020 | Citrate cycle (TCA cycle) | 10 | 579 | 25 | 3735 | 0.00 |
| ko01212 | Fatty acid metabolism | 13 | 579 | 39 | 3735 | 0.00 |
| ko00650 | Butanoate metabolism | 9 | 579 | 23 | 3735 | 0.01 |
| ko00380 | Tryptophan metabolism | 11 | 579 | 34 | 3735 | 0.01 |
| ko00072 | Synthesis and degradation of ketone bodies | 5 | 579 | 10 | 3735 | 0.01 |
| ko00310 | Lysine degradation | 12 | 579 | 39 | 3735 | 0.01 |
| ko04110 | Cell cycle | 24 | 579 | 99 | 3735 | 0.01 |
| ko00240 | Pyrimidine metabolism | 20 | 579 | 79 | 3735 | 0.02 |
| ko04146 | Peroxisome | 17 | 579 | 65 | 3735 | 0.02 |
| ko03430 | Mismatch repair | 7 | 579 | 19 | 3735 | 0.02 |
| ko04914 | Progesterone-mediated oocyte maturation | 17 | 579 | 67 | 3735 | 0.02 |
| ko04145 | Phagosome | 25 | 579 | 109 | 3735 | 0.02 |
| ko00220 | Arginine biosynthesis | 6 | 579 | 16 | 3735 | 0.03 |
| ko01210 | 2-Oxocarboxylic acid metabolism | 5 | 579 | 12 | 3735 | 0.03 |
| ko00480 | Glutathione metabolism | 10 | 579 | 34 | 3735 | 0.03 |
| ko00330 | Arginine and proline metabolism | 10 | 579 | 34 | 3735 | 0.03 |
| ko04217 | Necroptosis | 22 | 579 | 95 | 3735 | 0.03 |
| ko03440 | Homologous recombination | 10 | 579 | 36 | 3735 | 0.04 |
| ko00983 | Drug metabolism - other enzymes | 7 | 579 | 22 | 3735 | 0.04 |
| ko00980 | Metabolism of xenobiotics by cytochrome P450 | 8 | 579 | 27 | 3735 | 0.05 |
| ko00900 | Terpenoid backbone biosynthesis | 6 | 579 | 18 | 3735 | 0.05 |
| ko00010 | Glycolysis / Gluconeogenesis | 11 | 579 | 42 | 3735 | 0.05 |
S gene number: the number of significant differentially expressed mRNAs which match to a KEGG term; TS gene number: the number of significant differentially expressed mRNAs which have KEGG annotations; B gene number: the number of detected mRNAs which match to a KEGG term; TB gene number: the number of all detected mRNAs which have KEGG annotations