Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2018 Jun 27;16:58. doi: 10.1186/s12915-018-0526-3

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© Hayden et al. 2018

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

PMC Copyright notice

Fig. 5 — Neuronal survival is compromised in YAC128 1:3 CS co-cultures. DIV21 WT and YAC128 co-cultures were fixed at DIV21 and stained for MAP2 and DARPP32 (D32). (a) Sample fields of view at 20X objective (scale bar = 100 μm). The numbers of (Bi) MAP2+ and (Bii) DARPP32+ neurons per field of view are reduced in YAC128 1:3 co-cultures. (Biii) The proportion of DARPP32+ neurons (# DARPP32+ divided by # MAP2+) surviving at DIV21 is also significantly lower in YAC128 1:3 co-cultures [n = 30 fields of view from three independent cultures; two-way ANOVA with Bonferroni post-hoc analysis; *p < 0.05, ***p < 0.001]