Fig. 2.

Evaluation of DeepCRISPR for on-target efficacy prediction. a, b Comparison of sgRNA on-target efficacy predictions in a classification schema for various datasets, i.e., hct116 cell line, hek293t cell line, hela cell line, hl60 cell line, and the overall testing dataset. c Comparison of training loss for two different DeepCRISPR classification models. d Leave cell type out comparison of sgRNA on-target efficacy prediction in a classification schema. e Comparison of sgRNA on-target efficacy predictions in a regression schema for various datasets, i.e., hct116 cell line, hek293t cell line, hela cell line, hl60 cell line, and the overall testing dataset. f Leave cell type out comparison of sgRNA on-target efficacy prediction in a regression schema. g Comparison of sgRNA on-target efficacy predictions in an independent dataset with Spearman correlation