Table 1.

Objective-specific interventions and comparators

Objectives	Intervention	Comparator
To assess the efficacy of taxanes in comparison to anthracyclines as NACT	Taxanes	Anthracyclines
	Taxanes with anthracyclines
To assess the efficacy of targeted therapy along with NACT	Targeted therapy with anthracyclines	Anthracyclines
	Targeted therapy with taxanes	Taxanes
	Targeted therapy with anthracyclines and taxanes	Anthracyclines and taxanes
To assess the efficacy of trastuzumab along with NACT	Trastuzumab with anthracyclines	Anthracyclines
	Trastuzumab with taxanes	Taxanes
	Trastuzumab with anthracyclines and taxanes	Anthracyclines and taxanes
To assess the efficacy of Bevacizumab along with NACT	Bevacizumab with anthracyclines	Anthracyclines
	Bevacizumab with taxanes	Taxanes
	Bevacizumab with anthracyclines and taxanes	Anthracyclines and taxanes
Network Meta-analysis	All possible and feasible pairs of regimen comparison

NACT- Neoadjuvant Chemotherapy