Table 4.
Comparison albumin excretion rate (AER), albumin creatinine ratio (ACR), and glomerular filtration rate (GFR) of nondiabetic controls, diabetic controls, and diabetic rats treated with MB, metformin, and insulin rats after a 5-week study (n = 6 in each group). Values are expressed as mean ± SEM.
| Parameters | Groups | ||||
|---|---|---|---|---|---|
| NC | DC | MB | INS | MTF | |
| AER (mg/day) | 0.024 ± 0.01 | 0.29 ± 0.03# | 0.17 ± 0.01∗ | 0.15 ± 0.01∗ | 0.19 ± 0.03∗ |
| ACR | 8.10 ± 013 | 27.03 ± 1.13# | 15.72 ± 1.50∗ | 13.48 ± 0.84∗ | 19.23 ± 0.28∗ |
| GFR (mL/min/100 g) | 33.5 ± 0.5 | 24.8 ± 1.3# | 33.7 ± 1.5∗ | 37.9 ± 1.3∗ | 30.9 ± 2.1∗ |
# p < 0.05 by comparison with nondiabetic control; ∗p < 0.05 by comparison with diabetic control.