Table 5.
Effects of MB on MDA concentrations and activities of SOD and GPx in kidney tissues of non-diabetic controls, diabetic controls, and diabetic rats treated with MB, metformin, and insulin. Values are expressed as mean ± SEM.
| Parameter measured | Treatment | Kidney |
|---|---|---|
| MDA (nmol·g−1 protein) | NC | 0.994 ± 0.020 |
| DC | 4.21 ± 0.12# | |
| INS | 1.1 ± 0.01∗ | |
| MTF | 1.19 ± 0.01∗ | |
| MB | 1.14 ± 0.01∗ | |
|
| ||
| SOD activity (pg/mL) | NC | 13.43 ± 0.76 |
| DC | 6.01 ± 0.09# | |
| INS | 9.89 ± 0.10∗ | |
| MTF | 10.11 ± 0.02∗ | |
| MB | 10.08 ± 0.05∗ | |
|
| ||
| GPx activity (ng/mL) | NC | 2137.31 ± 0.03 |
| DC | 1703.491 ± 0.03# | |
| INS | 2062.21 ± 0.02∗ | |
| MTF | 2125.75 ± 0.01∗ | |
| MB | 21370.37 ± 0.03∗ | |
# p < 0.05 by comparison with nondiabetic control; ∗p < 0.05 by comparison with diabetic control.