Table 2.
Group | Weight (gram) | Temperature (0c) | ||||
---|---|---|---|---|---|---|
D0 | D4 | % Change | D0 | D4 | % Change | |
CON | 25.76±1.17 | 21.65±0.94 | -13.55 | 35.85±0.38 | 33.15±0.33 | -7.51 |
GT200 | 26.78±1.34 | 24.73±1.41 | -7.80a1b3e1 | 36.65±0.28 | 35.10±0.15 | -4.21a1b3e2 |
GT400 | 27.37±1.01 | 26.37±1.16 | -3.67a2b3 | 36.50±0.25 | 35.58±0.17 | -2.50a3b2 |
GT600 | 28.51±0.56 | 28.46±0.81 | -0.20a3b2 | 36.60±0.23 | 36.30±0.48 | -0.81a3 |
CQ25 | 28.02±1.11 | 30.95±1.10 | 10.55a3 | 36.32±0.34 | 36.82±0.25 | 1.40a3 |
| ||||||
CON | 27.78±0.49 | 24.04±0.53 | -11.14 | 36.75±0.31 | 34.25±0.26 | -6.80 |
BF200 | 28.91±0.48 | 26.81±0.42 | -7.25b3e1 | 37.35±0.21 | 35.53±0.16 | -4.85b3e1 |
BF400 | 29.24±0.31 | 28.09±0.24 | -3.91a2b3 | 37.45±0.21 | 36.02±0.30 | -3.83a2b3 |
BF600 | 27.93±0.48 | 27.77±0.60 | -0.61a3b3 | 36.90±0.24 | 36.00±0.33 | -2.45a3b3 |
CQ25 | 27.07±0.70 | 30.23±0.99 | 11.60a3 | 36.80±0.43 | 37.45±0.21 | 1.80a3 |
| ||||||
CON | 26.33±1.15 | 22.44±0.97 | -12.20 | 36.30±0.53 | 33.55±0.33 | -7.54 |
CF200 | 26.85±0.98 | 24.15±1.24 | -10.29b3 | 36.53±0.40 | 34.30±0.48 | -6.12b3 |
CF400 | 27.60±0.62 | 25.43±0.67 | -7.91b3 | 36.70±0.33 | 35.05±0.43 | -4.51a1b3 |
CF600 | 28.41±0.63 | 27.20±0.60 | -4.27a3b3 | 36.80±0.41 | 35.55±0.40 | -3.39a2b3 |
CQ25 | 28.10±0.82 | 31.39±0.76 | 11.83a3 | 36.70±0.40 | 37.28±0.26 | 1.65a3 |
| ||||||
CON | 26.93±0.73 | 23.65±0.90 | -10.72 | 36.45±0.25 | 33.10±0.50 | -9.21 |
AF200 | 27.74±0.85 | 25.04±0.91 | -9.82b3 | 36.90±0.31 | 33.80±0.34 | -8.41b3 |
AF400 | 26.92±0.79 | 24.60±0.76 | -8.61b3 | 36.35±0.36 | 33.70±0.34 | -7.29b3 |
AF600 | 28.61±0.61 | 26.34±0.65 | -7.96b3 | 37.08±0.40 | 34.52±0.43 | -6.92b3 |
CQ25 | 28.32±0.63 | 31.21±0.68 | 10.22a3 | 37.00±0.35 | 37.90±0.23 | 2.45a3 |
Data are expressed as mean ± SEM (n=6); a, compared to CON; b, compared to CQ 25 mg/kg; c, compared to 200 mg/kg; d, compared to 400 mg/kg; e, compared to 600 mg/kg; 1p< 0.05; 2p<0.01, 3p<0.001; CON, negative control; GT = crude extract, BF = n-butanol fraction, CF = chloroform fraction, AF = aqueous fraction, and CQ = chloroquine; D0 = pretreatment value on day zero, D4 = posttreatment value on day four; numbers (25,200,400,600) refer to dose in mg/kg.