Table 1.
Details of different groups imaged at the various sites (Germany, USA, Denmark, and Belgium; see text for details).
| PET imaging site | Experimental group | Control group |
|---|---|---|
| Site number 1, Germany (Technical University of Munich) | HAEO (n = 11) | HAECGER (n = 11) |
|
| ||
| Site number 2, USA (University of California, Irvine) | ∗ Sev0.25% (n = 8) | ∗ HAECsev (n = 8) |
| ∗ Sev0.5% (n = 8) | ||
| ∗ Des1% (n = 7) | ∗ HAECdes (n = 7) | |
|
| ||
| Site number 3, Denmark (Rigshospitalet, Copenhagen University Hospital) | CB (n = 7) | HAECDEN (n = 7) |
|
| ||
| Site number 4, Belgium (University Hospital of Liege) | UWS (n = 65) | HAECBEL (n = 28) |
| MCS (n = 65) | ||
| EMCS (n = 17) | ||
∗ indicates that both absolute CMRglc (aCMRglc) and quantified CMRglc (qCMRglc) were obtained from the USA site, enabling comparison between them (see Figures 1(b) and 1(c)). aCMRglc: absolute CMRglc with blood sampling of the tracer FDG supply to the brain; qCMRglc: calibration of quantified comparing qCMRglc with aCMRglc for HAEC only eqs. (1 and 2); HAEC: healthy people awake with eyes closed (control condition); HAEO: healthy people awake with eyes open; Des1%: healthy people sedated with 1% desflurane; Sev0.25%: healthy people sedated with 0.25% sevoflurane; Sev0.50%: healthy people sedated with 0.5% sevoflurane; CB: awake people with congenital blindness; UWS: patients who were unresponsive wakefulness syndrome; MCS: patients who were in a minimally conscious state; EMCS: patients who emerged from MCS.