Table 2.
Articles included in the review, organized in chronological order of publication: authors, year, type of cancer, treatment modality, lesion classification instrument, study groups, number of patients, form of administration, and duration of the intervention.
| Reference | Type of cancer | Treatment modality | Injury classification tool | Study groups | Number of patients | Form of administration | Duration of the intervention |
|---|---|---|---|---|---|---|---|
| [11] | Head and neck cancer | QT | The WHO scale | Group 1. Chamomile-Prophylaxis (radiotherapy) Group 2. Chamomile Prophylaxis (chemotherapy) Group 3. Therapeutic Chamomile |
Group 1: 20 Group 2: 46 Group 3. 32 |
Mouthwash | 14 consecutive days |
|
| |||||||
| [12] | NC | QT | The WHO scale | Group 1: Placebo Group 2: Chamomile |
Group 1: 82 Group 2: 82 |
Mouthwash | 14 consecutive days |
|
| |||||||
| [13] | NC | QT | The WHO scale | Group: Chamomile | Group: 01 | Oral | 30 consecutive days |
|
| |||||||
| [14] |
Head and neck cancer | RT | The WHO scale | Group 1. Chamomile gel during the radiotherapy Group 2. Chlorhexidine digluconate Group 3. Chamomile gel after radiotherapy |
Group 1: 7 Group 2: 7 Group 3: 8 |
Topic | NC |
|
| |||||||
| [8] | Leukemia | TCH | The WHO scale | Group 1. Control Group 2. the 0.5% Group 2 Chamomile: Chamomile to 1% Group 3. the chamomile 2% |
Group 1: 10 Group 2: 10 Group 3: 10 Group 4: 10 |
Mouthwash | 5 consecutive days |
|
| |||||||
| [15] | Head and neck cancer | RT | The WHO scale | Group 1. Chamomile Group 2. Honey Group 3. Water |
Group 1: 35 Group 2: 35 Group 3: 35 |
Mouthwash | 15 consecutive days |
|
| |||||||
| [16] | Leukemia | TCT | The toxicity scale INC | Group 1. Placebo Group 2. Mint and Chamomile |
Group 1. 33 Group 2. 27 |
Mouthwash | NC |
|
| |||||||
| [17] | Gastric cancer | QT | The WHO scale | Group 1. Cryotherapy-Control Group 2. Cryotherapy with chamomile |
Group 1. 18 Group 2. 20 |
Topic | 22 consecutive days |
|
| |||||||
| [18] | Non-Hodgkin lymphoma | RT | Visual analogue scale sterile caliper | Group 1. Placebo Group 2. Triamcinolone Acetonide Group 3. Chamomile |
Group 1: 15 Group 2: 14 Group 3: 14 |
Oral | 10 consecutive days |
|
| |||||||
| [19] | Acute lymphoblastic leukemia | QT | The WHO scale | Single group: Chamomile | Single group: 31 | Mouthwash | 14 consecutive days |
|
| |||||||
| [20] | Acute lymphoblastic leukemia | QT | The WHO scale | Group 1: (Allopurinol, sucralfate, sodium bicarbonate, and semi-saline serum) Group 2: Chamomile |
Group 1: 31 Group 2: 31 |
Mouthwash | 14 consecutive days |
UI: uninformed; ↓: reduction; ↑: increase; TNF: tumor necrosis factor; IL: interleukin; HCT: hematopoietic cell transplantation; QT: chemotherapy; RT: radiotherapy; WHO: World Health Organization.