Table 3.

Clinical trials on the effectiveness of Matricaria.

Reference	Intervention	Jadad score	Results
[11]	Kamillan Liquidum solution made from chamomile flowers	4	↓ in the appearance of oral mucositis in 85% of the patients ↑ immediate relief of painful symptomatology ↑ reepithelialization of the desquamated tissue
[12]	Chamomile concentrate	5	Degree of oral mucositis < in the male gender No significant difference (treated versus placebo groups)
[13]	Infusion with 8 g of dried flowers with 20 ml of water	-	↓ in the oral mucositis grade III on the 13th day 30th day complete absence of mucositis
[14]	Gel with 3% of chamomile extract	3	↓ discomfort and severity of oral mucositis ↓ treatment time It was not effective in preventing
[8]	Oral antiseptic with 0.5%, 1%, and 2% of chamomile extract	5	Significant results found in the dosage of 1% ↓ incidence ↓ intensity of injuries ↓ oral mucositis duration
[15]	3 ml of chamomile mouthwash added to the half cup of water	3	↓ pain ↓ incidence
[16]	Oral antiseptic with 1% of chamomile extract and 1% of	5	↓ pain ↓ dryness of the oral cavity ↓ dysphagia
[17]	Ice with 400 ml of water and 10 g of chamomile flowers	4	↓ incidence of oral mucositis ↓ painful symptomatology ↓ presence of ulcerations
[18]	Chamomile Orobase	5	↓ intensity of pain ↓ the size of the lesion
[19]	15 drops of chamomile solution diluted in a glass of water	0	↓ incidence ↓ gravidity
[20]	30 ml of chamomile	4	↓ incidence ↓ gravidity

↓: reduction; ↑: increase.