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. Author manuscript; available in PMC: 2018 Jun 27.
Published in final edited form as: Gynecol Oncol. 2017 Jan 7;144(3):613–620. doi: 10.1016/j.ygyno.2017.01.009

Figure 1. HDAC10 is deleted in many ovarian tumors, and loss of HDAC10 correlated with sensitivity to cisplatin.

Figure 1

A. The chromosome 22 locus containing the HDAC10 gene is shown, and deletions found as a common variant were shown in blue at the bottom. B. Frequency of HDAC10 alteration in tumor types is indicated. Data were taken from the TCGA database using software from CBioPortal. C. Some of the tumors in the TCGA ovarian cancer dataset were linked with information about cisplatin sensitivity of the tumor. The status of the HDAC10 gene was indicated in columns. D. HDAC10 mRNA abundance in tumor samples from cisplatin-sensitive tumors (blue) was compared to mRNA abundance in cisplatin-resistant tumors (red). The statistical test used was an unpaired student’s t-test.