Table 3.
Evaluation of mean apparent permeability (Papp) and the absorption enhancement ratio (R) of curcumin (CUR) with polyvinylpyrrolidone (PVP) at different ratios across Caco-2 cell monolayers after 2 h incubation1.
| Formulation | Absorption |
PAPP × 10-6 (cm/s) | R | |
|---|---|---|---|---|
| μg | % | |||
| CUR | 10.00 ± 0.42c | 8 | 4.96 ± 0.21c | – |
| CUR/PVP (1:6) | 21.44 ± 3.42b | 17.16 | 10.64 ± 1.69b | 2.14 |
| CUR/PVP (1:9) | 66.00 ± 13.58a | 52.80 | 32.74 ± 6.74a | 6.60 |
1Data are expressed as mean ± SE. a-c Values within columns with different superscripts differ significantly (P < 0.05); n = 3.