Table 2.

Composition of the combined repeat tract [(TG)_v (TCTG)_w (CCTG)_x (NCTG)_y (CCTG)_z] of non-expanded, normal alleles in 34 DM2 positive patients determined by sequencing analysis.

Combined repeat size (bp)	(TG)v	(TCTG)w	(CCTG)x	(NCTG)y	(CCTG)z
	v	w	x	y	z
134	21	8	5	3	7
	21	8	5	3	7
	21	8	5	3	7
	21	8	5	3	7
	19	9	5	3	7
	19	9	5	3	7
	19	9	5	3	7
	19	9	5	3	7
	17	10	5	3	7
	17	10	5	3	7
	21	7	6	3	7
	19	8	6	3	7
138	23	8	5	3	7
	23	8	5	3	7
	21	9	5	3	7
	21	9	5	3	7
	21	9	5	3	7
	21	9	5	3	7
	21	9	5	3	7
	21	9	5	3	7
	21	9	5	3	7
	21	9	5	3	7
	19	10	5	3	7
	19	10	5	3	7
	19	10	5	3	7
	23	7	6	3	7
	21	8	6	3	7
142	23	9	5	3	7
	21	10	5	3	7
	21	10	5	3	7
	25	7	6	3	7
152	22	8	8	5	6
156	22	9	8	5	6
168	18	10	23	–	–

Indices v, w, x, y, and z denote the number of the specific repeat elements. While y and z were constant (y = 3, z = 7) throughout all 31 patients with repeat sizes of 134, 138, or 142 bp, x was found to be binary with x = 5 being about five times more frequent than x = 6. In contrast, v and w were highly variable with v ranging from 17 to 25 and w ranging from 7 to 10 in all 34 patients. The interruption of the two CCTG tracts by (NCTG)_y was found to comprise three tetraplets in the high abundance alleles and five in two of the three large normal alleles (152 and 156 bp). The largest allele of 168 bp showed no interruption (y = 0) but 23 contiguous CCTGs.