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. 2018 Jun 12;32:164–171. doi: 10.1016/j.ebiom.2018.05.033

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© 2018 The Authors

This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).

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Fig. 3 — Results of CDH13 rs4783244 × long-term sleep status interaction on LVM index at 10-year follow-up. LVM index means left ventricular mass index. X-axis represents the copies of the G allele in CDH13 rs4783244 and Y- axis represents LVM index (g/m^2.7). The median of sleep durations at baseline and follow-up were 8.5 and 8 h, respectively. Subjects were classified into four groups according to the median of sleep durations at baseline and follow-up, respectively. A, sleep duration >8.5 h/day at baseline (long) and > 8.0 h/day at follow-up (long); B, > 8.5 h/day at baseline (long) and ≤ 8.0 h/day at follow-up (short), C, ≤ 8.5 h/day at baseline (short) and > 8.0 h/day at follow-up (long), and D, sleep duration ≤8.5 h/day at baseline (short) and ≤ 8.0 h/day at follow-up (short). Red dotted line represents the 95% confidence intervals and black line represents the regression line. The interaction p value is listed for LVM index. P value for interaction in the liner regression model was adjusted for baseline age, follow-up time, sex, CDH13 genotype, SBP, TG, HDL-C, FBG, HOMA-IR, BMI, smoking, total energy intake and physical activity at follow-up.