Table 2.

Associations of the six SNPs with the cardiac-traits and adiponectin levels.

Gene	SNP	Position	Allele	MAF		IVSDT (cm)	LVEDD (cm)	LVPWT (cm)	LVM (g)	LVM index (g/m2.7)	Adiponectin (ug/ml)#
CDH13	rs4783244	intron	T/G*	0.325	β	−0.020	−0.076	−0.008	−6.774	−1.781	0.238
					p	0.028	0.023	0.314	0.004	0.001	8.07× 10−7
ADIPOQ	rs10937273	5′ near gene	A*/G	0.388	β	−0.010	−0.052	−0.006	−3.761	−0.889	0.031
					p	0.287	0.111	0.442	0.107	0.103	0.515
ADIPOQ	rs6773957	3’ UTR	G/A*	0.426	β	−0.014	0.008	−0.018	−1.840	−0.577	0.012
					p	0.098	0.805	0.018	0.416	0.275	0.800
WDR11FGF	rs3943077	Between the 2 genes	G/A*	0.370	β	0.011	0.008	−0.004	1.156	−0.286	0.066
					p	0.215	0.814	0.616	0.616	0.595	0.163
CMIP	rs2925979	intron	T/C*	0.406	β	−0.010	−0.008	0.006	−0.719	−0.029	0.040
					p	0.257	0.802	0.466	0.758	0.958	0.410
PEPD	rs889140	intron	A*/G	0.491	β	0.008	0.022	0.004	2.045	0.769	0.027
					p	0.364	0.495	0.562	0.371	0.150	0.576

Abbreviation: MAF, minor allele frequency; IVSDT inter ventricular septal diastolic thickness, LVEDD left ventricular end-diastolic diameter, LVPWT left ventricular posterior wall thickness, LVM left ventricular mass.

Minor allele/major allele. *Allele with higher adiponectin levels.

#Variables were ln-transformed before analysis.

β means linear regression coefficients adjusted for sex, age and BMI.

Values in bold were significant at a Bonferroni-corrected threshold of p ≤ .008.