Table 3.

Difference in Mean Therapeutic Misconception between Decliners and Acceptors

Therapeutic Misconception Score Mean (SD) Range (1, 5)	Acceptors, N=171 Mean (SD)	Decliners, N=15 Mean (SD)	P-Value*
This study is designed to give everyone the type of treatment and amount of treatment that best fits with his or her individual needs.	4.04 (1.20)	3.93 (1.16)	0.592
When designing research, researchers must be sure that each person in the study will get the best treatment available for that person’s individual needs, just as though they were being treated by their own personal doctor.	4.28 (1.13)	4.07 (1.28)	0.472
Researchers always try to provide each person in a study the treatment that best meets that person’s individual needs.	4.04 (1.22)	3.40 (1.18)	0.031
The purpose of the experimental study is to provide the best treatment available for me and others in the study.	4.20 (1.23)	3.93 (1.49)	0.634
Research studies are designed primarily to help those people who participate in them rather than primarily to help future patients with the same disease.	2.47 (1.36)	2.33 (1.45)	0.644
A researcher’s most important task is to make sure that the research will help the people who participate.	3.58 (1.41)	3.80 (1.52)	0.450
The reason I was asked to be in this study is that it will provide me with the best available treatment.	4.08 (1.20)	3.20 (1.42)	0.012
The treatment I am getting in this study is definitely the best treatment for me.	4.33 (0.89)	3.13 (1.13)	<.0001
Being in a research study almost always provides the best possible treatment for a sick person.	3.32 (1.20)	3.13 (1.55)	0.755
By participating in a research study, people will get the best treatment for their medical problems.	3.56 (1.14)	2.80 (1.52)	0.049
Mean Individualization Score	4.12 (1.05)	3.80 (1.01)	0.168
Mean Purpose Score	3.42 (0.99)	3.36 (1.01)	0.840
Mean Benefit Score	3.82 (0.86)	3.07 (1.16)	0.012
Overall Mean Therapeutic Misconception Score	3.79 (0.77)	3.37 (0.85)	0.042

^*Wilcoxon Two-Sample Test

Note: Higher scores indicate greater TM