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. 2016 Nov 22;145(3):607–625. doi: 10.1017/S0950268816002673

Table 2.

Infection characteristics estimated by the TSIR model. The approximate generation time of each infection determines the discrete time step used in the TSIR model

Infection TSIR time step  Inline graphic Mean reporting proportion Mean βs R2
Measles Biweekly 0·2207 0·004 (0·002) 5·41 (1·52) 0·92
(95% CI 0·2197–0·2217)
Mumps Monthly 0·1277 0·034 (0·007) 10·53 (0·78) 0·98
(95% CI 0·1274–0·1281)
Rubella Biweekly 0·2807 0·017 (0·002) 4·72 (0·18) 0·99
(95% CI 0·2788–0·2825)
Varicella Biweekly 0·80 0·092 (0·02) 1·79 (0·06) 0·93
(95% CI 0·7996–0·8)
Scarlet fever Biweekly 0·80 0·006 (0·001) 1·75 (0·06) 0·91
(95% CI 0·8–0·8)
Pertussis Monthly 0·0533 0·001 (0·0001) 24·65 (5·21) 0·93
(95% CI 0·0531–0·0533)

TSIR, Time-series susceptible-infected-recovered; CI, confidence interval.

Inline graphic is the estimated mean proportion of susceptibles in the population (95% CIs in parentheses, derived from the profile likelihood using the χ2 distribution with 1 degree of freedom). Mean reporting proportion is the mean of the time-varying reported rates estimated using locally varying regression of cumulative births on cumulative cases (standard deviation of the time-varying rates in parentheses). Mean βs is the mean value of the seasonal transmission rates estimated via the TSIR model (maximum standard error in parentheses). The R2 values (on a log scale) for the TSIR fit are measured as 1 – [residual deviance/null deviance].