Unique stem cell line identifier |
WAe001-A-17 |
Alternative name(s) of stem cell line |
H1-p53(R248W/R248W) and 1P6 |
Institution |
The University of Texas Health Science Center at Houston, Houston, Texas, USA |
Contact information of distributor |
Dung-Fang Lee dung-fang.lee@uth.tmc.edu
|
Type of cell line |
Human embryonic stem cell line |
Origin |
Human |
Additional origin info |
Sex: Male |
Cell Source |
H1 hESCs |
Clonality |
Clonal |
Method of reprogramming |
N/A |
Genetic Modification |
Yes |
Type of Modification |
Homozygous R248W mutation of TP53 on exon 7 |
Associated disease |
Li-Fraumeni syndrome; cancers |
Gene/locus |
17p13.1; TP53 exon 7 |
Method of modification |
Transcription activator-like effector nucleases (TALEN) |
Name of transgene or resistance |
N/A |
Inducible/constitutive system |
N/A |
Date archived/stock date |
2017/12 |
Cell line repository/bank |
Human Pluripotent Stem Cell Registry (https://hpscreg.eu/user/cellline/edit/WAe001-A-17) |
Ethical approval |
Cell lines were used according to institutional guidelines. UTHealth approval number: SCRO-16-01 |