TABLE 12.
ABNORMAL SEROLOGY | SENSITIVITY (%) | SPECIFICITY (%) | PPV (%) | NPV (%) | POSITIVE LIKELIHOOD RATIO | NEGATIVE LIKELIHOOD RATIO |
---|---|---|---|---|---|---|
ESR (≥50mm/hr) | 57.14 | 56.14 | 24.24 | 84.21 | 1.30 | 0.76 |
ESR (Miller) | 57.14 | 43.86 | 20.00 | 80.65 | 1.02 | 0.98 |
CRP (>3.0mg/dL) | 57.14 | 73.68 | 34.78 | 87.50 | 2.17 | 0.58 |
Platelets (>400,000/μL) | 64.29 | 96.49 | 81.82 | 91.67 | 18.32 | 0.37 |
IL-6 (>5.00pg/mL) | 45.45 | 94.59 | 71.43 | 85.37 | 8.41 | 0.58 |
ESR or CRP | 78.57 | 43.86 | 25.58 | 89.29 | 1.40 | 0.49 |
ESR (Miller) or CRP | 71.43 | 35.09 | 21.28 | 83.33 | 1.10 | 0.81 |
CRP or plts | 78.57 | 71.93 | 40.74 | 93.18 | 2.80 | 0.30 |
Plts or IL-6 | 85.71 | 71.93 | 42.86 | 95.35 | 3.05 | 0.20 |
CPR or IL-6 | 85.71 | 75.44 | 46.15 | 95.56 | 3.49 | 0.19 |
CDU (any sign) or plts | 68.75 | 84.21 | 55.0 | 90.57 | 4.35 | 0.37 |
CDU (halo only) or plts | 35.71 | 91.23 | 50.0 | 85.25 | 4.07 | 0.70 |
Abnormal ESR (Miller) defined as >age/2 for males and >(age+10)/2 for females55.
ESR = Westergren erythrocyte sedimentation rate
CRP = c-reactive protein; plts = platelets
IL-6 = interleukin-6
CDU = color duplex ultrasonography.