Table 1.

Most differentially expressed miRNAs: blood versus colorectal epithelia

miRNA	Small RNA sequencing				RT-qPCR
	Average read counts		AUC	Fold difference	AUC	Fold difference
	Blood (n = 25)	Epithelia (n = 95)
Blood markers			Blood to epithelia		Blood to epithelia
hsa-miR-144-3p	20,435	47	1	439	1	3988
hsa-miR-144-5p	6580	38	1	171	1	888
hsa-miR-486-5p	52,729	546	1	97	1	238
hsa-miR-451a	416,628	4417	1	94	1	948
hsa-miR-363-3p	3911	97	1	40	1	119
hsa-miR-20b-5p	885	27	1	32	1	826
hsa-miR-106a-5p	475	24	1	20	0.97	7
hsa-miR-32-5p	949	59	1	16	1	23
hsa-miR-185-5p	8994	575	1	16	0.998	23
hsa-miR-101-3p	39,580	2654	1	15	0.998	33
hsa-miR-15b-5p	1057	79	1	13	1	28
hsa-miR-142-5p	4160	315	1	13	0.998	38
hsa-miR-16-5p	11,786	1265	1	9	1	35
hsa-miR-15a-5p	571	66	1	9	0.998	19
hsa-miR-15b-3p	376	53	1	7	0.976	12
Epithelial markers			Epithelia to blood		Epithelia to blood
hsa-miR-200a-5p	1	1295	1	1385	0.988	1143
hsa-miR-200b-3p	19	34,828	1	1817	1	2207
hsa-miR-200a-3p	4	9900	1	2281	0.95	1551
hsa-miR-203a	1	3007	1	3395	0.992	8360
hsa-miR-375	5	18,612	1	3711	0.972	41,033

P values for all comparisons between blood and colorectal epithelial were <.0001