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. 2018 Jun 27;4(6):eaar8409. doi: 10.1126/sciadv.aar8409

Fig. 3. Changes in inflammatory cytokine concentrations in nonhuman primate serum samples after treatment with 7C1 siRNA nanoparticles.

Fig. 3

(A) Treatment with Tie2 siRNA. (B) Treatment with Luc control siRNA. Statistically significant differences (P < 0.05, t test) are denoted by the * symbol. G-CSF, granulocyte colony-stimulating factor; GM-CSF, granulocyte-macrophage colony-stimulating factor; IFN-α, interferon-α; TNF-α, tumor necrosis factor–α. BLC, brain-derived neurotrophic factor; I-TAC, IFN-inducible T cell alpha chemoattractant; MCP-1, monocyte chemoattractant protein-1; MIP1-α, macrophage inflammatory protein-α; BNDF, brain-derived neurotrophic factor; PDGF-BB, platelet derived growth factor-BB.