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. 2018 Jun 12;9(45):27698–27707. doi: 10.18632/oncotarget.25498

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Copyright: © 2018 Yasumizu et al.

This is an open-access article distributed under the terms of the Creative Commons Attribution License 3.0 (CC BY 3.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

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(A) The number of C4-2AT6 cells with overexpression of PKM2 under normoxia 24hr or 48hr after administration of RAD001. RAD001 exhibited low cytotoxicity towards C4-2AT6 with overexpression of PKM2 under normoxia. ^*p< 0.05 compared to intact C4-2AT6 cells. (B) Western blotting showed PKM2 expressions was up-regulated in C4-2AT6 transfected with PKM2 plasmids.