Table 1. GI50 of STF-62247 in leukemic cell lines.
Cell line | 24 h | 48 h | 72 h | 96 h |
---|---|---|---|---|
S1T | 43.0 | 29.3 | 21.2 | 14.9 |
MT-2 | 42.9 | 15.1 | 7.62 | 6.43 |
Jurkat | 83.9 | 37.6 | 27.9 | 19.3 |
Cell lines were incubated at 2 × 105 cells/mL in the presence of indicated concentrations (μM) of STF-62247 for 24–96 h. Values of GI50 (compound concentration that reduced cell growth by 50%) are shown for various time points.