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Transcriptomic profiling of aged peritoneal macrophages. (a) Aged peritoneal macrophages display numerous transcriptomic changes, which suggest perturbations in various gene ontology (GO) processes (b) and pathway maps (c). (d) Interactome analysis revealed numerous overconnected transcription factors (TFs) whose known gene targets were overrepresented in the genes we identified as dysregulated in aged versus young macrophages.
