Fig. 4.
Age affects human peripheral blood mononuclear cell (PBMC) and plasma oxysterol signatures. (a-b) There was a significant negative correlation between age and PBMC 7-KC levels, PBMC C-triol levels, and PBMC 24-HC levels in healthy human subjects. (c-d) There was a significant positive correlation between age and plasma C-triol levels and a trend towards a positive correlation between age and plasma 4β-HC levels. Open circles depict individual data points; lines depict the best-fitting linear regression line (a-d; r = Pearson product-moment correlation coefficient; rs = Spearman rank-order correlation coefficient).