Table 2.

Expression profiling of lipid-related genes in aged and young macrophages.

Cellular function	Gene symbol	Fold changea	P-valueb
Biosynthesis	Fads2	−1.545	0.050
	Fads3	1.299	0.050
	Fdft1	−3.831	0.050
	Fdps	−1.885	0.050
	Hmgcs2	3.122	0.050
	Prkaa2	2.773	0.046
	Scd1	−1.895	0.050
Elimination	Cyp11a1	−9.342	0.050
	Cyp7b1	2.515	0.046
	Cyp27a1	−1.473	0.050
	Hadhb	−1.984	0.050
	Lpl	1.496	0.050
	Tbxas1	1.249	0.050
Leukotriene signaling	Lta4h	−1.314	0.050
	Alox5ap	−1.919	0.050
Transport	Apoa1	−6.985	0.046
	Apof	−6.089	0.050
	Slc16a6	−1.459	0.050
	Slc27a1	−1.659	0.050
	Slc27a3	−4.402	0.050
	Stard4	−1.306	0.050
Uptake	Cxcl16	−1.927	0.050
	Olr1	−2.340	0.050
	Pcsk9	−1.903	0.050
	Stab2	−3.008	0.046
Other or multiple functions	Adfp	2.102	0.050
	Alox15	5.797	0.050
	Fabp4	1.338	0.050
	Nr0b2	−3.911	0.037
	Nr1h3	−1.561	0.050

^aAged versus young peritoneal macrophages; negative fold-change reflects decreased expression in aged macrophages relative to young macrophages.

^bSignificant by 2-tailed Mann-Whitney U test.