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. 2018 Feb 23;70(3):1061–1073. doi: 10.1007/s10616-018-0197-5

Table 3.

Percentage of caspase-3 activity of glioblastoma (C6) cells after CCDP (cisplatin), ε-VNF (ε-viniferin) and CDDP/ε-VNF (cisplatin + ε-viniferin) treatment at different times and concentrations

12 h 24 h 48 h 72 h
Viability (%) Caspase activity (%) Viability (%) Caspase activity (%) Viability (%) Caspase activity (%) Viability (%) Caspase activity (%)
Control 99.6 0.4 95.3 4.6 94.7 5.3 93.9 6.0
CDDP (35 µΜ) 99.6 0.4 91.2 8.8 95.5 4.5 85.6 14.4
CDDP (5 μM) 99.7 0.3 94.7 5.3 89.4 10.6 95.3 14.6
ε-VNF (130 μM) 99.4 0.6 86.1 13.9 94.4 5.6 85 14.9
ε-VNF (95 μM) 99.2 0.8 96.1 3.9 95.7 4.4 84.5 15.4
CDDP/ε-VNF (16.25 + 127.5 μM) 99.3 0.7 91.0 9.0 98.1 1.9 89.6 10.3
CDDP/ε-VNF (13.25 + 95 μM) 99.4 0.6 93.7 6.3 95.7 4.4 84.5 15.5