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. 2018 Jun 15;9(46):28116–28130. doi: 10.18632/oncotarget.25565

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Copyright: © 2018 Angelucci et al.

This is an open-access article distributed under the terms of the Creative Commons Attribution License 3.0 (CC BY 3.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

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GCSCs showed irregular nuclei (N) mainly formed by euchromatin with marginated heterochromatin and prominent nucleoli (n) (A, B). Rough endoplasmic reticulum (RER), mitochondria (m), vesicles (v) and intermediate filaments (IF) were visible in the cytoplasm (C, D). Lipid droplets (L), primary and secondary lysosomes (ly and ly^*, respectively) were observed (A, B and D). Plasma membranes showed microvilli (mv) (A) and loose cell-cell contacts (square in B and at higher magnification in D). Scale bars = 2 μm.